Image: Chicago Sports & Spine

30. Jaundice

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One of the telltale signs of pancreatic cancer is jaundice, which is a yellowing of the eyes and skin. According to the American Cancer Society, almost all cases of pancreatic cancer begin with jaundice. Jaundice is a result of bilirubin buildup ( a substance that is made in the liver). Usually, it’s excreted by the liver in bile, however when the bile duct becomes blocked it can build up in the body, usually do to cancers beginning in the head of the pancreas. As the cancer spreads, it usually moves to the liver which results in jaundice.